The Gunners will make the short journey to Wembley for the semi-final with the Citizens but will be without several first-team stars.
David Ospina, Danny Welbeck, Shkodran Mustafi and Lucas Perez are all missing as they continue to nurse injury problems.
Wenger may use a three-man defence like he did for Monday's 2-1 win over Middlesbrough.
Hector Bellerin and Theo Walcott will be pushing for recalls as they try to help the Gunners reach the FA Cup final.
Provisional squad: Cech, Martinez, Macey, Bellerin, Holding, Gabriel, Koscielny, Mertesacker, Monreal, Gibbs, Maitland-Niles, Coquelin, Xhaka, Ramsey, Oxlade-Chamberlain, Ozil, Walcott, Iwobi, Sanchez, Giroud.