The Gunners are set to begin their Europa League campaign without the likes of Petr Cech, Laurent Koscielny, Aaron Ramsey, Mesut Ozil, Granit Xhaka, Danny Welbeck and Alexandre Lacazette.
Wenger has opted to omit them from his matchday squad as he looks to use some of his fringe players to get the job done against Koln, who are currently bottom of the Bundesliga.
Jack Wilshere could feature for the first time in over a year for Arsenal, having spent last term on loan with Bournemouth, while Alexis Sanchez has also been included in the squad as he looks to get back to full match fitness.
Striker Olivier Giroud should be given the nod to start after being restricted to a place on the bench in Arsenal’s Premier League engagements so far this term.
Midfield duo Francis Coquelin and Santi Cazorla remain sidelined with hamstring and Achilles injuries respectively.