The Villa boss looks set to include Christian Benteke, Gabby Agbonlahor and Charles N'Zogbia from the start again after they dovetailed well in the 2-2 draw against West Brom.
Andreas Weimann and Darren Bent are also in contention - giving Lambert ample firepower to overturn the 3-1 first-leg deficit at Villa Park.
Weimann has returned to training and is available after sitting out the derby draw at The Hawthorns because of illness.
Brad Guzan could keep his place in goal if Shay Given fails to recover from the hamstring trouble which has kept him out of the squad for two matches.
Nathan Baker is definitely out after sustaining a hamstring injury in the early stages at The Hawthorns.
Richard Dunne is making good progress with his fitness and is expected to return to contention soon, although Lambert hinted it would be too much of a risk to include the experienced defender tonight after a six-month groin injury lay-off.