The 28-year-old American goalkeeper has been at Villa Park since 2008 and struggled for first-team action during his first spell at the club. However, after he left Villa Park at the end of last season, Paul Lambert immediately took him back after he arrived from Norwich to replace Alex McLeish during the summer.
And Guzan has since flourished under the Scot to become the first-team regular ahead of Republic of Ireland veteran Shay Given.
As a result, Guzan is now hoping to put in performances similar to last weekend's, when he helped preserve Villa's lead in the 2-1 win against West Ham, between now and the end of the campaign.
"This was a club that gave me an opportunity when I first came from America," he said on the club's website.
"For Americans to come to England and have that chance and to have someone take a chance on you was fantastic. As we know, not too many Americans come over.
"They are starting to come over more regularly now but a few years ago there were only a handful of us and guys that came before me set the bar.
"For me to repay Aston Villa for giving me that opportunity and saying 'yes we'll take a chance on him', that is what lit that fire within me and I want to give more to the club."