The on-loan Manchester City defender wasn't eligible to play against Arsenal in the Carling Cup due to the terms of his loan agreement, although Coyle said he wouldn't have been fit had he been available.
The Belgium international limped off during the 2-0 defeat to Sunderland at the weekend but Coyle says he expects the 20-year-old to return to light training this week.
"He couldn't have played against Arsenal because of the agreement with Manchester City but he's getting better," the Wanderers boss told Bolton News. "I would think Dedryck would be a part of things on Saturday.
"It will be good to have him back because he is really improving."
Coyle went on to say that he had been impressed with the likes of Boyata, David Ngog and David Wheater this season, despite the club's league position, and says he wants some of his more experienced players to stand up and be counted at the Liberty Stadium on Saturday.