Spearing hobbled out of the action shortly before half-time as Wanderers secured the 2-1 win at Bristol City that moved them into the play-off places, two points and two places above their midweek opponents.
Freedman expects the on-loan Liverpool midfielder's bruised toe to be healed in time to play at the King Power Stadium but knows he has an able deputy in weekend replacement Medo Kamara.
"Jay has had a bruised nail for a number of weeks and it's not sore at all when he's got a pair of flip-flops on but with these fancy new boots they have these days that squash it, he got a kick and it was sore," the manager told the Bolton News
"I think he will be fine for Tuesday, it was just very uncomfortable for him. But I thought Medo was fantastic when he stepped in."
Craig Davies came off the bench to net the winner from the penalty spot at Ashton Gate and could push for a start in attack.
David Wheater (calf) and Tyrone Mears (illness) are set to remain on the sidelines alongside long-term absentee Mark Davies (knee).