The Whites have been linked with a January swoop for the ex-Huddersfield Town man, who has been out of favour at the Riverside Stadium this season.
Clayton, who turned 29 on Sunday, started 13 Championship matches under former boss Garry Monk but has featured just once under Tony Pulis.
That was as a late substitute in a 1-0 home defeat to Fulham and reports have indicated Clayton will be allowed to leave in the January transfer window.
Pulis’ desire to cut an ‘over-sized’ and ‘imbalanced’ Boro squad has prompted many to conclude that the player’s days on Teesside are numbered.
Clayton scored six goals in 42 Championship appearances for Leeds in 2011/12.
Cardiff remain unhappy with Derby's decision to postpone Sunday's Sky Bet Championship game at Pride Park.
Dundee United boss Csaba Laszlo has been left hoping for St Mirren to slip up in the race to seal promotion to the Ladbrokes Premiership.
Crewe will consider starting Chris Dagnall when they host Forest Green on Tuesday.