The American star is the latest big name to confirm his participation and he will be expecting to challenge a field that also contains Masters champion Danny Willett, defending champion Adam Scott and Spanish star Sergio Garcia.
Fowler, currently ranked 14th in the world, led last year's event for the first two days before tailing off and ended up in a tie for sixth as Scott eventually came out on top.
"Next week is really going to turn into probably one of our finest Honda Classics yet," executive director Ken Kennerly said in the Sun Sentinel.
"We're building on the tremendous momentum we had last year where we had over 200,000 people that came out to PGA National."
Also playing in the tournament that runs between February 23-26 are: Justin Thomas, Martin Kaymer, Brooks Koepka and Zach Johnson, while previous Honda Classic winners Padraig Harrington, Russell Henley, Camilo Villegas, Mark Wilson, Michael Thompson and Mark Calcavecchia will also be present.