Frankie Bunn's development squad will travel to the Yorkshire Payments Stadium to take on Vill Powell's men on December 6.
The match will be open to the public, with adult tickets costing £4 and children's entry costing £2.
Kick off is at 7.45pm and the match will consist of three 30-minute periods - at the request of Huddersfield Town.
Brighouse are close to the bottom of the Evo-Stik North table, having won just five of their 20 matches.
They sit above Goole AFC and Ossett Albion just outside of the relegation zone, but did beat Colne last time out.