Faye was forced out of last week's win at Millwall with a calf strain and replaced by Jack Hobbs, who is expected to continue.
Fathi and Gedo, signed from Egyptian side Al-Ahly on loan until the end of the season, are hoping to be included.
"They arrived with us on Thursday and we'll take them down to Brighton with us," Bruce told a press conference.
"They're travelling with us, but they're straight off a plane and it's going to be a big ask of them.
"We'll have a training session with them (on Friday) and see what sort of shape they're in."
Midfielder David Meyler has been passed fit after having stitches in a cut knee last week and is likely to continue.
Bruce has no other injury or suspension worries as the Tigers look to climb back into the top two.
Hull last week