Bruce, who on Thursday was hit with a misconduct charge by the Football Association, was dismissed as manager of the Black Cats in November 2011 despite overseeing a relatively stable two-and-a-half-year spell at the club.
The 52-year-old got the best out of Darren Bent, who scored 24 league goals in Bruce's first season, and the club finished 13th and 10th in the table before he was replaced by Martin O'Neill.
A mid-table finish seems a long way off for the club now given their poor start, which has put them in real danger of relegation.
But when asked whether Saturday's game at the KC Stadium took on any more significance because of his history with Sunderland, Bruce said: "No. No. Not any more. It would be nice to win though."