The two sides go head-to-head at the Nou Camp on Saturday with Los Blancos boasting a six-point lead at the top of La Liga.
Zinedine Zidane's men defeated Sporting Gijon 2-1 on Saturday, while Barca's inconsistent run continued as they were held to a 1-1 draw at Real Sociedad.
As a result, Vazquez sees no reason why Real Madrid cannot go to the home of their rivals and secure a positive result.
The 25-year-old said: "We go into it in very good form, top of the table. Let's hope that we pick up a good result at the Camp Nou.
"We're raring to go and are really confident. If we win it'll see us take a major step towards the La Liga title, but it's the most consistent side that wins the league and not whoever comes out on top in the Barca-Madrid game. We're on the right track, but we've got to keep going and look to win more games.
"At Real Madrid there are big demands and the dressing room is aware that the aim is to win everything going."