The left-back signed a two-and-a-half-year deal at Sixfields after leaving Rochdale this week.
Aaron Pierre (thigh), Aaron Phillips (thigh), Daniel Powell (hip), George Smith (ankle) and Leon Barnett (Achilles) are all out for boss Jimmy Floyd Hasselbaink.
Captain Marc Richards left the club on a free transfer this week and joined Swindon.
Dons boss Robbie Neilson will see his squad boosted in numbers, with Marcus Tavernier in line to make his debut.
The winger, brother of former Dons defender James Tavernier, joined the club this week on loan from Middlesbrough, as Gboly Ariyibi returned to his parent club Nottingham Forest.
Osman Sow and Ike Ugbo are back in contention.
Sow has completed a three-match suspension while it was agreed Ugbo, on loan from Chelsea, would return to Stamford Bridge and miss the AFC Wimbledon game last weekend.
Nemanja Matic believes Manchester United boss Jose Mourinho's driven methods and high expectations will bring the club more success.
Cardiff remain unhappy with Derby's decision to postpone Sunday's Sky Bet Championship game at Pride Park.