Matty Kennedy made his first start for Pompey since November and could retain his place alongside centre-backs Matt Clarke and Christian Burgess, who came away unscathed during the 2-0 loss at Shrewsbury following recent injury issues.
Jamal Lowe looks set to start in attack despite a 19-game goal drought but Stuart O’Keefe is doubtful after missing the last two matches with an adductor injury, with Ben Close set to keep his place in the starting line-up if he fails to recover.
Milan Lalkovic (Achilles), Kal Naismith and Jack Whatmough (both knee) are long-term absentees.
AFC Wimbeldon will be looking to build on their first home victory in more than two months.
Manager Neal Ardley could be boosted by the return of defender Paul Robinson.
The 35-year-old centre-back missed the Dons’ 2-1 victory over Bradford with a back issue, but he could return on Boxing Day.
Midfielder Harry Forrester is back in the squad after serving a one-game ban following his red card against Wigan.
Rangers manager Steven Gerrard is weighing up a move for Liverpool full-back Jon Flanagan, reports claim.
Scottish champions Celtic are reportedly ready to offer full-back Calvin Miller a new deal before sending him out on loan.
Everton target Jack Wilshere has sparked a scramble for his signature after confirming he is leaving Arsenal this summer.
Tottenham's hopes of landing Wilfried Zaha have been hit by the news Crystal Palace have offered him a bumper new deal to stay.
Ryan Giggs says Gareth Bale would be the perfect fit for Manchester United but has doubts over whether he will leave Real Madrid.
Manchester City's attempts to sign Riyad Mahrez could be in doubt again as reports claim Leicester only want a straight cash deal.