The visitors looked as though they had earned themselves a deserved point when Ryan Watson curled in a sublime free-kick, cancelling out Kane Wilson’s first-half opener for Exeter.
But Jake Taylor fired home a superb 20-yard strike in the first minute of stoppage time to seal maximum points for the fourth-placed Grecians.
“I am delighted with the win,” Tisdale said. “That was as close to winter football as you can get, the pitch made it very difficult against a very, very good side. I thought Barnet played really well today.
“We defended well and attacked well and missed some chances that could have put the game to bed at 1-0, but we got that injury-time winner with a very controlled finish from Jake Taylor.
“I have been told that was our 100th goal of 2017, so that was a nice little round figure to finish the year off with and we are all very, very pleased.
“We have been very, very productive at home and I am not sure how we have fared, but I think we’ve been one of the most effective home teams in the Football League and I believe this was my 600th game today, so that was another nice round figure.
“But they count for nothing until the first week in May and we will see where we sit then. It all adds up to it and builds what will hopefully be a successful year. It won’t be perfect, but it’s about dozens and dozens of small, good decisions made minute after minute.”
Barnet boss Mark McGhee was left deflated after seeing his side’s good performance go unrewarded.
He said: “We played quite well today, the shape we played worked well enough for us. We can always play better but here is another game that we have lost.
“Eventually we have to turn these into wins. If we keep improving, then we will have a chance of winning a game.
“We have to look at the performance first. In the first half we certainly edged it in terms of the play and possession but we lost a soft goal.
“To go in 1-0 down at half-time was disappointing. It really asked a question about their spirit and determination to get back into the game.
“They answered it terrifically well, they showed the spirit and the energy and we got a deserved equaliser. From that moment on, we were sensible.
“We tried to keep it tight but we were undone by a long ball up to the edge of our box which we don’t deal with well enough.
“So that is not about systems, but it’s about basic defending so we ended up losing a game which we didn’t feel we deserved to lose.”
Colchester will hand late fitness tests to Ryan Jackson and Brandon Comley prior to their clash with Yeovil.
Arsenal secured their place in the quarter-finals of the Europa League following their 3-1 defeat of AC Milan at the Emirates Stadium on Thursday.
Danny Welbeck scored twice against AC Milan to toast his England recall by sending Arsenal into the last eight of the Europa League.
Ipswich striker Joe Garner will not play again this season after it emerged he suffered a fractured skull against Sheffield United last week.