The goalkeeper limped off with a groin problem just 33 minutes into the Boxing Day draw with Mansfield and is awaiting the results of scans.
Ben Killip made his English Football League debut and the 22-year-old is set to continue in McKeown’s absence.
Scott Vernon and JJ Hooper both came off the bench against the Stags and are pushing for a start.
Accrington skipper Seamus Conneely is hoping to recover from a recurrence of a groin injury in time to feature.
Right-back Conneely was an unused substitute in the Boxing Day defeat at Carlisle, but could return as John Coleman’s side bid to avoid a fifth straight league defeat.
Defender Jordan Thorniley remains doubtful after missing out at Carlisle due to a similar problem, while Erico Sousa is pushing for a recall after his recent leg injury.
Accrington have lost their last five games in all competitions and are chasing their first league win on the road since October.
Pedro stepped off the bench to send Chelsea into the FA Cup semi-finals after they beat Leicester 2-1 at the King Power Stadium on Sunday evening.
RB Leipzig came from behind at the Red Bull Arena to end a run of four winless games and defeat Bundesliga leaders Bayern Munich 2-1 on Sunday.