Both Coutinho and Daniel Sturridge missed that exit at the hands of Zenit as they were cup-tied but they are available to play at Wigan.
Sturridge will require a late fitness test as he has not yet fully recovered from the thigh injury that was sustained in month's 2-2 draw with Manchester City.
The Reds are likely to be without Raheem Sterling for the trip as the young star is currently being rested after a busy season, although Brendan Rodgers has denied he is suffering from burn-out.
Meanwhile, Rodgers has warned his side it will not be easy against the Latics.
"I watched Wigan last week and it will be a tough game for us," he said. "But after the performance levels against Swansea and Zenit, we just want to keep that going.
"The key for us is to really focus on these next 11 games and make sure we finish what has probably been a mix of a season by showing there have been real benefits from the learning that has taken place and to really kick on and get consistent results.
"Every game for us is a cup final. We need to continue to show that warrior spirit. That is vital for us."