The Red Devils last won the league title in 2013 and they have struggled since Sir Alex Ferguson decided to retire that year.
Under David Moyes, Louis van Gaal and Jose Mourinho, United have finished seventh, fourth, fifth and sixth.
Mourinho helped his side win the League Cup and Europa League last season but he is now ready to help his team compete in the Champions League and Premier League.
Victor Lindelof, Romelu Lukaku and Matic have all joined the club this summer and the latter is expecting a title charge, which you can back using your free bet.
He told reporters: "We have to rest well because we have a very important game on Sunday against West Ham.
"It's the start of the Premier League and it's very important for us. As you know the Premier League is the main target.
"There is a lot of games, it's a long season but I expect us to do well."
Mourinho's men will be hoping for a good start to the season this month and they will take on West Ham United, Swansea City and Leicester City before the end of the month.