The Blues are currently third in the Premier League table but they could leapfrog rivals Manchester United, with the Red Devils not in action until Monday.
Chelsea are enjoying a solid run of late and they are unbeaten in their last nine matches but they have drawn their last three games in all competitions.
Boss Antonio Conte has no fresh injury concerns, with midfielder Ross Barkley still working his way back to full fitness.
Saturday’s game may come too soon for him but Leicester will be doing all they can to secure back-to-back wins in the league.
They beat Huddersfield Town last time out and striker Jamie Vardy has recovered from a groin injury after missing the FA Cup tie with Fleetwood.
Defenders Wes Morgan and Danny Simpson remain out with hamstring problems and Leicester will have their work cut out as they look to end a four match losing run to Chelsea.
A goal apiece from James Tomkins and Luka Milivojevic handed Crystal Palace a crucial 2-0 win over Huddersfield at the John Smith's Stadium on Saturday evening.
Manchester United bounced back from their Champions League exit as they beat Brighton 2-0 at Old Trafford on Saturday night to reach the FA Cup semi-finals.
Tottenham reached the FA Cup semi-finals after they cruised to a 3-0 victory over Swansea in their quarter-final clash at the Liberty Stadium on Saturday.
Premier League basement club West Brom squandered the lead as they suffered a 2-1 defeat to Bournemouth at the Vitality Stadium on Saturday.
Chesterfield boss Jack Lester felt his side were unlucky not to claim all three points after their 1-1 draw at Cheltenham.
New Swindon manager Phil Brown revelled in his side's victory at Cambridge in his first game in charge.