The Blues have already equalled their own record of 29 wins in one top-flight campaign, but one more success will see them surpass that total.
Antonio Conte's men have won five league matches in a row to see off the title challenge of Tottenham and they will fancy their chances of securing another win against a Sunderland side that are already guaranteed to finish bottom of the division.
Conte is yet to confirm whether captain John Terry will start or be used as a substitute during his Stamford Bridge finale.
The 36-year-old is set to leave Chelsea during the summer and his chances of starting the match could depend on whether David Luiz recovers from a niggling knee injury.
Sunderland will head into the match looking for only their seventh league win of the campaign, while they have only taken five points from their last 13 matches.
David Moyes' men have only won twice in the league this calendar year, although both those successes have come on the road against Crystal Palace and Hull.
The Black Cats have also won at Stamford Bridge in the recent past, securing a 2-1 success in 2014 thanks to goals from Connor Wickham and Fabio Borini.
Sunderland have a growing injury list heading into the match, with Lamine Kone and Didier Ndong emerging as the latest fitness doubts, as they are both struggling with dead legs.
The likes of Papy Djilobodji, Victor Anichebe and Whabi Khazri are already on the sidelines, as Moyes looks set to field a patched up team for Sunderland's Premier League swansong.