On that occasion, the Magpies pulled off a shock 5-1 victory despite having already been relegated. In fact, Spurs have only won twice on their last 10 Premier League visits to St James' Park.
The Magpies have won just one opening league match in the last nine seasons and that ironically came against Tottenham, a 2-1 success in 2012.
Rafa Benitez has admitted his frustration at a lack of new additions this summer, but three new signings are in contention to make their debuts on Sunday.
Jacob Murphy, Florian Lejeune and Javier Manquillo are all available for the Newcastle boss. Former Crystal Palace man Dwight Gayle is available despite a recent hamstring injury, but American DeAndre Yedlin is sidelined.
After back-to-back title challenges, many are looking to Tottenham to collect silverware this season and they will expect to start well - Spurs have won all of their Premier League fixtures against promoted sides in the last two seasons.
Harry Kane is likely to lead the line and the England striker needs just one goal to reach 100 for Spurs, although he has never scored a Premier League goal in August.
Tottenham will be without injured full-back Kieran Trippier, after he suffered an ankle injury in last weekend's friendly win over Juventus, while Danny Rose and Erik Lamela are still missing with long-term injuries.