Striker Taylor is struggling with a knee injury while defender Sawyer is recovering from an Achilles problem suffered against Mansfield last weekend. Both men missed the 1-1 draw at Wycombe on Tuesday.
Midfielder Connor Smith remains sidelined with an ankle injury but could be back in action in the coming weeks after returning to first-team training.
Cardiff loanee Matt Kennedy and midfielder Antoni Sarcevic may feature after both returned from injury lay-offs on against Wycombe.
Morecambe boss Jim Bentley has no fresh injury concerns for the trip.
Bentley saw Alex Kenyon return to action following knee surgery in the reserves' clash with Bradford on Wednesday but this game is likely to come too soon for the midfielder.
The Shrimps boss made four changes to his starting line-up for the midweek defeat at home to Newport and may shuffle his pack once again.
Michael Duckworth will hope to start after he came on for Liam Wakefield early in the second half of the loss.