The Baggies are currently eighth and still have hopes of making next season's Europa League, but they will need to bounce back from back-to-back defeats - against Crystal Palace and Everton.
West Brom have a poor record against the Gunners, with West Brom's just one win in the last 13 competitive meetings came at The Hawthorns, although that did come last season.
The home team will be without James Morrison because of an ankle injury, while winger Matt Phillips is still nursing a hamstring problem and remains sidelined for a fourth game.
The Gunners have lost three of their last four league fixtures, a run that has seen them slip to fifth in the table - although they do have two games in hand on fourth-placed Liverpool.
Arsene Wenger could have Mohamed Elneny available for selection, after the midfielder made a quicker than expected recovery from an ankle problem.
Alex Oxlade-Chamberlain and Kieran Gibbs are both expected to under late fitness tests on knocks suffered in the FA Cup victory over Lincoln.