The Pilgrims, who are now unbeaten in five, took the lead with their first effort on goal after 39 minutes as Graham Carey picked out Ruben Lameiras on the edge of the box and his low strike beat Ben Williams at his near post.
Carey doubled Plymouth’s lead on the stroke of half-time with a sensational goal, striking a dropping ball over his shoulder from the left edge of the area which looped over Williams and into the far corner.
But the Seasiders were back in it after 55 minutes through Colin Daniel, who latched onto a clearance from a corner and drilled in low from 20 yards.
Blackpool dominated after that goal but Plymouth came within inches of killing the game after 68 minutes as David Fox’s header hit the far post.
Gary Bowyer’s side pushed late on and got their reward as Solomon-Otabor struck a low effort from 15 yards which crept in at the near post.
Rangers manager Steven Gerrard is weighing up a move for Liverpool full-back Jon Flanagan, reports claim.
Scottish champions Celtic are reportedly ready to offer full-back Calvin Miller a new deal before sending him out on loan.
Everton target Jack Wilshere has sparked a scramble for his signature after confirming he is leaving Arsenal this summer.
Tottenham's hopes of landing Wilfried Zaha have been hit by the news Crystal Palace have offered him a bumper new deal to stay.
Ryan Giggs says Gareth Bale would be the perfect fit for Manchester United but has doubts over whether he will leave Real Madrid.
Manchester City's attempts to sign Riyad Mahrez could be in doubt again as reports claim Leicester only want a straight cash deal.