It is not the first time the 22-year-old has been linked with a return to Italy since arriving from Inter Milan with Roma and Lazio known to be keen, but on each occasion the player has dismissed the rumours.
Milan are the latest club to be linked after president Silvio Berlusconi hinted he could be a target, but Santon says he is happy where he is and has ruled out a move away.
"I have had a year and a half here. I really enjoy it. I am happy at the club," he revealed. "This is really important for a young player. We are a young team here and we are growing together. That will only make us stronger in the long-term."
Santon had his problems on the injury front in his first season but is now Newcastle's regular right-back and has no intention of returning to Serie A.
"The team give me confidence to play my game," he added. "If you play when you are stressed you can't give 100 per cent. But when you are settled as a group you can do well.
"I know I can do better than now, though. And when we have all of our players fit, we know we can do better as a team."