The win over the Russians took their tally for their European campaign to 23 goals, the second-highest in the competition’s group stage history behind Paris St-Germain’s 25 this year.
The Reds have scored 32 goals in an unbeaten nine-match run since losing to Tottenham in late October and are hitting top form at precisely the time they began to run out of gas 12 months ago.
That should hopefully bode well for when the Champions League restarts in February.
Asked if his side would be a threat in the last 16, Klopp said: “If we perform like this tonight, if we are that clinical, then yes. But we had the same players already and they didn’t score (in some previous games).
“If we perform like this then it is obviously a threat, 100 per cent. If you see how Dom Solanke performed in Stoke, how Daniel Sturridge performed when he came on, he could have scored two or three, he made a goal for Sadio, that’s good.”
Philippe Coutinho led the way with his first Liverpool hat-trick with Sadio Mane scoring twice, with Roberto Firmino and Mohamed Salah getting the others.
It meant Liverpool topped Group E and avoided the likes of PSG, Barcelona and Roma but could still draw Bayern Munich, Juventus or Real Madrid.
Javi Gracia said it was always going to be an uphill battle for Watford after conceding so early against Liverpool on Saturday.
Schalke 04 boss Dominico Tedesco paid tribute to goalkeeper Ralf Fahrmann after his 76th-minute penalty save proved crucial in a 1-0 win over Wolfsburg.
Mattia De Sciglio stunned that Juventus were shocked to be held to a goalless draw with SPAL on Saturday.
Sunderland have suspended midfielder Darron Gibson with immediate effect after he was charged with drink driving.
Jose Mourinho's recent bad frame of mind was still present despite Manchester United beating Brighton 2-0 at Old Trafford on Saturday, a result that puts them into the last four of the FA Cup.
Mohamed Salah continued his astounding goalscoring form on Saturday, hitting four goals as Liverpool thrashed Watford 5-0 at Anfield.