Red Devils boss David Moyes has found the going tough since taking over from Sir Alex Ferguson in the summer, and for the first time in years United have stuttered through the first few months of the campaign.
Despite their poor start the former Everton boss is hopeful he will be able to help them retain the title.
United currently sit eight points behind Arsenal in the race for the Premier League crown, but Toure believes that Liverpool are now a greater threat to City’s title ambitions than their local rivals.
He said in The Sun: “United will find it hard to defend the title since they have a new manager and are really struggling.
“Liverpool are a big threat at the moment because they have a strong squad and their strikers – Luis Suarez and Daniel Sturridge – are scoring goals at will.”
You can back Liverpool to win their first Premier League title with your free bet.
Steve Cotterill has been sacked by Birmingham the club have announced - with Garry Monk in pole position to replace him as manager.
Bundesliga top-four rivals RB Leipzig and Borussia Dortmund had to settle for a share of the points with a 1-1 draw at the Red Bull Arena.
Steve Cotterill has left Birmingham with Garry Monk in pole position to replace him as manager, Press Association Sport understands.
Walsall manager Jon Whitney stressed that his whole Saddlers side deserved to be praised following their 3-0 win at Southend United.
Paris St Germain forward Neymar has undergone 'successful' foot surgery.
Chris Coleman was pleased with the character shown by his Sunderland side - but frustrated to have to settle for a point in their 1-1 draw at Millwall.