Pochettino gave short shrift to Sissoko’s comments following the defeat in Monaco that Tottenham would prefer to play Europa League games at White Hart Lane rather than Wembley.
The Argentinian has proven himself ruthless with players that fail to toe the line as the sales of Andros Townsend, Emmanuel Adebayor, Paulinho, Etienne Capoue and Younes Kaboul have shown in the past.
Pochettino suggested Sissoko is not fulfilling his potential.
“It is not frustrating for me. It is about football. We can see in football different things happen,” Pochettino said.
“If you sign a player and you expect something, and you do not find what you expect and if another deserves to be involved, like (Georges-Kevin) Nkoudou or (Vincent) Janssen – why? Because we paid money we need to put the player to play?
“Of course he needs to work hard and show in the future he deserves to be involved in the team.”
Former Swansea caretaker boss Alan Curtis believes Carlos Carvalhal deserves great credit for the impact he has had at the club.
West Ham have issued life bans to five pitch invaders who came onto the playing surface in the defeat to Burnley last time out.
Brighton centre-half Shane Duffy says his game has come on leaps and bounds thanks to Chris Hughton and Martin O'Neill.
Bournemouth midfielder Lewis Cook says he is ready to take his chance with England should he be handed his senior debut.
Tottenham will have to make a massive offer to land Wilfried Zaha, according to former Crystal Palace chairman Simon Jordan.
Nigel Clough believes keeping Burton in the Championship this season will surpass the achievements of last term's survival.
Garry Monk has challenged his Birmingham players to maintain the high standards they set when beating Hull in their last league game.
Former manager Mark Warburton claims Rangers need to be patient with Graeme Murty or suffer the 'same old problems'.