The 22-year-old has been a strong performer for the Ligue 1 club this season and also caught the eye with Cameroon in the Confederations Cup last summer.
Reports in Africa claim the Baggies have made a 19m euros bid, which would suggest that Zambo Anguissa has been identified as Alan Pardew’s top midfield target in the January transfer window.
The ex-Reims star has made 13 league starts and 19 appearances in total, but has not scored for Marseille this season.
He scored against Australia in last summer’s Confederations Cup and once in World Cup qualifying, but Cameroon didn’t make it to Russia 2018.
Colchester will hand late fitness tests to Ryan Jackson and Brandon Comley prior to their clash with Yeovil.
Arsenal secured their place in the quarter-finals of the Europa League following their 3-1 defeat of AC Milan at the Emirates Stadium on Thursday.
Danny Welbeck scored twice against AC Milan to toast his England recall by sending Arsenal into the last eight of the Europa League.
Ipswich striker Joe Garner will not play again this season after it emerged he suffered a fractured skull against Sheffield United last week.