The Juve legend and Italy international has called a press conference at the Allianz Stadium in Turin.
Buffon, 40, helped his club win their seventh straight Serie A title last weekend and they have already won the Coppa Italia for the fourth consecutive year.
The former Parma star is set to make his 640th appearance against Hellas Verona on Sunday and reports claim he will confirm it will be his last.
His agent, Silvano Martina told the Italian media: ‘There will never be another Gigi.
‘I can’t add anything more because he will reveal what he’s going to do next to the press [on Thursday].’
Bayer Leverkusen have signed keeper Lukas Hradecky from Eintracht Frankfurt ahead of Bernd Leno's likely exit.