The Blades' 3-0 Boxing Day victory over Scunthorpe kept them top of the pile but Wilson was concerned it may have come at a cost with striker Miller and defender Collins both forced off.
Former Crewe man Miller did not emerge for the second half with a knee problem while a facial injury brought Collins' afternoon to a premature end.
Wilson would not confirm whether it would be possible for Collins to play with a protective mask while Miller will be handed a late fitness test.
Defender Tony McMahon will also be missing for the Blades as he serves a one-match suspension following his fifth yellow card of the season against the Iron.
Goalkeeper Mark Howard (thigh) and defender Lescinel Jean-Francois (knee) are working their way back to fitness but are unlikely to be risked against a side with just one win all year.