Kane bagged his 97th and 98th top-flight goals in Tottenham's 4-0 win over Everton, to surpass Teddy Sheringham as the north London club's all-time leading scorer in the Premier League.
The England international now has 20 goals this term to leave him just 11 shy of the leading number of strikes in a 38-game Premier League season - a record held by Alan Shearer, Cristiano Ronaldo and Luis Suarez - and 14 away from Andy Cole and Shearer's joint haul of 34 during a 42-match campaign.
Asked if Kane could break the record with 15 games still to play, Pochettino said: "He can do everything because of his mentality and how he is as a professional. He can achieve all he wishes and he wants.
"It is unbelievable the way that he is able to work and his willingness. He is always thinking to try to improve, improve, improve, score goals and improve for the team.
"His mentality is always collective and that is always important to explain. He has scored a lot of goals but his mentality is to help the team, work for the team, and that is what makes him a special player."