The American star scored the equaliser and then set up Emmanuel Adebayor for the winner at the Britannia Stadium to keep alive the club's hopes of landing a top-four place this season.
The 30-year-old has now hit seven goals this season following his deadline-day move from Fulham and AVB is well aware just how important a member of his squad the experienced frontman is.
"It was an amazing game from Clint Dempsey. He has the instincts of a deadly striker," Villas-Boas told talksport. "Today he scored and assisted Emmanuel Adebayor for his goal. It was a great performance by him. He is a player who deserves a lot of credit."
Dempsey himself was pleased with his contribution and is clearly enjoying his time at White Hart Lane.
"You always want to be a player that chips in with goals and assists," he said. "I'm glad I've scored some important goals this season and a few assists as well."