McCarthy changed all ten of his outfield players from the side that won 1-0 at Spurs last weekend for the trip to Manchester United on Tuesday night and Wolves were comfortably beaten 3-0.
The critics have been out in force since that defeat, including Arsenal boss Arsene Wenger, but McCarthy has clearly had enough and told them where to go.
He said: "I have got more integrity and honesty in that little finger than most of those who are accusing me. Whoever it is, I am not bothered.
"I go through the season and I complain not one jot about anybody. I try my best not to complain, I try my best not to get involved in anyone else's politics or football club or anything like that and I am not going to get involved.
"It is laughable. I have had lots of messages of support, not because anyone thinks I need it because of the decisions that I made, but because of some of the ridiculous, scathing, outrageous comments that have been made about me and what I did."